Density-level Decision Layer for Cryo-EM Programs

• Accepted inputs: reconstructed maps (.mrc / .map)
• Evaluation focus: map consistency, regional confidence, ligand pose support (if applicable) iMap-level review of density evidence for structural consistency and region-specific confidence. Where a ligand interpretation is provided, ligand pose support is assessed from density evidence only (not docking, pose generation, or simulation).
• Exclusions: no raw data processing, no particle picking, no map reconstruction, no full structure delivery iScope excludes micrograph preprocessing, particle picking/extraction, 3D reconstruction, and atomic model building/delivery. This service is a decision-oriented map assessment based on reconstructed cryo-EM maps.

• Executive Risk Memo with explicit assumption & uncertainty framing iDecision-focused document summarizing structural evidence quality and uncertainty.
• Quantitative structural consistency indicators iQuantitative measures describing density coherence and interpretability.
• Region-level confidence assessment iLocalized reliability estimates across spatial segments of the density map.
• Decision-impact summary suitable for internal review decks
• Standardized artifacts iRepeatable outputs designed for comparability across cases and internal auditability.
  • Risk Scorecard (standard rubric across cases)
  • Red-flag signature library (recurring failure modes)
  • Decision memo generator (consistent structure, fast turnaround)
• Applicable before downstream computational modeling (including FEP) or experimental commitment

• Engagement format: rapid triage, case review, or program support iFlexible scope based on a single decision point or broader program needs.
• Procurement-ready: one-off or repeat engagements under NDA iCan be set up as a single assessment or repeated work under an existing NDA.
• Decision timing: aligned to stage-gates and Go/No-Go checkpoints iDesigned to support internal decision points before further modeling or experiments.
• Commercial model: project-based billing, case-specific scope iPricing is scoped per case based on complexity and turnaround.
• Commercial path: paid pilots to annual team subscription to enterprise license (on-prem) as workflow adoption expands iStructured to start with a defined-scope pilot and scale into recurring subscriptions or enterprise licensing.

Built for industry decision workflows and lean team operations.

• Reconstructed maps only (no raw data required).
• Encrypted transfer options available.iSecure data transmission using industry-standard cryptographic protocols.
• Client data is segregated per engagement.iData isolation ensuring no cross-project access or commingling.
• No cross-project reuse or incorporation into shared datasets.
• No model training or data retention beyond the agreed scope.iDuration of stored client data prior to secure deletion.
• Default deletion within 30 days unless otherwise agreed.
• NDA available upon request.
• Designed to minimize IP exposure and align with client confidentiality requirements.